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|本期目录/Table of Contents|

菌群的生物节律现象及其临床意义(PDF)

《医学争鸣》[ISSN:1000-2790/CN:61-1060/R]

期数:
2019年05期
页码:
4-7
栏目:
专家论坛
出版日期:
2019-10-31

文章信息/Info

Title:
Biorhythmic phenomenon of microflora and its clinical significance
作者:
徐天成 裴丽霞 陈 璐 吴晓亮 耿 昊 周俊灵 易 越 孙建华
(南京中医药大学附属医院,江苏 南京 210029)
Author(s):
XU Tiancheng PEI Lixia CHEN Lu WU Xiaoliang GENG Hao ZHOU Junling YI Yue SUN Jianhua
Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing 210029, China
关键词:
肠道菌群生物节律时间医学
Keywords:
intestinal bacteria biological rhythm time medicine
分类号:
R37;Q939.93
DOI:
10.13276/j.issn.1674-8913.2019.05.002
文献标识码:
A
摘要:
生物节律现象广泛存在于各类生物体内,而菌群生物节律与宿主生物节律的关系是近年研究的热点 之一,研究层面从生态系统到分子机制一应俱全,并在多国开展了基于菌群— 宿主生物节律互作的临床试验研 究,相关成果对开发时间特异性疗法及微生物制剂具有重要意义。
Abstract:
Biological rhythm phenomenon widely exists in various organisms. The relationship between bacteria and host circadian biological rhythm is one of hot research subjects in recent years. The researches of different levels from molecular mechanism to ecological system are all available. The clinical trials of bacteria-host interaction based on biological rhythm have been carried out in many countries. The relevant achievements of those researches have great implications for the development of time-specific therapy and microbial preparations.

参考文献/References

[1] Sharp KH, Pratte ZA, Kerwin AH, et al. Season, but not symbiont state, drives microbiome structure in the temperate coral Astrangia poculata[J]. Microbiome, 2017, 5(1):120.
[2] Shoemaker KM, Moisander PH. Seasonal variation in the copepod gut microbiome in the subtropical North Atlantic Ocean[J]. Environ Microbiol, 2017, 19(8):3087-3097.
[3] Sánchez-Cañizares C, Jorrín B, Poole PS, et al. Understanding the holobiont: the interdependence of plants and their microbiome[J]. Curr Opin Microbiol, 2017, 38:188-196.
[4] Ren T, Boutin S, Humphries MM, et al. Seasonal, spatial, and maternal effects on gut microbiome in wild red squirrels[J]. Microbiome, 2017, 5(1):163.
[5] Franceschi C, Ostan R, Santoro A. Nutrition and inflammation: are centenarians similar to individuals on calorie-restricted diets?[J]. Annu Rev Nutr, 2018, 38 (1):329-356.
[6] Kong F, Deng F, Li Y, et al. Identification of gut microbiome signatures associated with longevity provides a promising modulation target for healthy aging[J]. Gut Microbes, 2019, 10(2):210-215.
[7] Biagi E, Franceschi C, Rampelli S, et al. Gut microbiota and extreme longevity[J]. Curr Biol, 2016, 26(11):1480-1485.
[8] Kong F, Hua Y, Zeng B, et al. Gut microbiota signatures of longevity[J]. Curr Biol, 2016, 26(18):R832-R833.
[9] Cuestazuluaga JDL, Corralesagudelo V, Velásquezmejía EP, et al. Gut microbiota is associated with obesity and cardiometabolic disease in a population in the midst of Westernization[J]. Sci Rep, 2018, 8(1):202-208.
[10] Paschos GK, FitzGerald GA. Circadian clocks and metabolism: implications for microbiome and aging[J]. Trends Genet, 2017, 33(10):760-769.
[11] Sorek M, Schnytzer Y, Ben-Asher HW, et al. Setting the pace: host rhythmic behaviour and gene expression patterns in the facultatively symbiotic cnidarian Aiptasia are determined largely by Symbiodinium[J]. Microbiome, 2018, 6(1):83.
[12] Tahara Y, Yamazaki M, Sukigara H, et al. Gut microbiotaderived short chain fatty acids induce circadian clock entrainment in mouse peripheral tissue[J]. Sci Rep, 2018, 8(1):1395.
[13] Gruber J, Kennedy BK. Microbiome and longevity: gut microbes send signals to host mitochondria[J]. Cell, 2017, 169(7):1168-1169.
[14] Yang Z, Huang S, Zou D, et al. Metabolic shifts and structural changes in the gut microbiota upon branchedchain amino acid supplementation in middle-aged mice[J]. Amino Acids, 2016, 48(12):2731-2745.
[15] Thaiss CA, Nobs SP, Elinav E. NFIL-trating the host circadian rhythm-microbes fine-tune the epithelial clock[J]. Cell Metab, 2017, 26(5):699-700.
[16] Watad A, Azrielant S, Bragazzi NL, et al. Seasonality and autoimmune diseases: the contribution the four seasons to the mosaic of autoimmunity[J]. J Autoimmun, 2017, 82(6):13-30.
[17] Skarke C, Lahens NF, Rhoades SD, et al. A pilot characterization of the human chronobiome[J]. Sci Rep, 2017, 7(1):17141.
[18] Stappenbeck TS. Assigning function to symbionts[J]. Nat Microbiol, 2018, 3(1):6-7.
[19] Neville BA, Forster SC, Lawley TD. Commensal Koch's postulates: establishing causation in human microbiota research[J]. Curr Opin Microbiol, 2018, 42:47-52.
[20] Quigley EMM. Are diets the answers to colon ills? Food, irritable bowel syndrome and the microbiome[J]. Curr Opin Gastroenterol, 2018, 34(2):103-104.
[21] Kundu P, Blacher E, Elinav E, et al. Our gut microbiome: the evolving inner self[J]. Cell, 2017, 171(7):1481-1493.
[22] Pitlik SD, Koren O. How holobionts get sick—toward a unifying scheme of disease[J]. Microbiome, 2017, 5(1):64.
[23] Magnúsdóttir S, Thiele I. Modeling metabolism of the human gut microbiome[J]. Curr Opin Biotechnol, 2018, 51:90-96.
[24] Westfall S, Lomis N, Prakash S. Longevity extension in Drosophila through gut-brain communication[J]. Sci Rep, 2018, 8(1):8362.
[25] Han B, Sivaramakrishnan P, Lin CCJ, et al. Microbial genetic composition tunes host longevity[J]. Cell, 2018, 173(4):1058.

备注/Memo

备注/Memo:
基金项目:国家自然科学基金(81473748,81804193);江苏省中医院高峰人才项目(Y2018RC05)
通信作者:孙建华。教授,主任医师。Tel:13914722816,E-mail:drjhsun@sina.com
作者简介:徐天成。硕士生(导师孙建华)。研究方向:从事针灸临床及效应机制研究。Tel:13951683100, E-mail:xtc24203@163.com
更新日期/Last Update: 2019-10-31