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从陈香美院士团队诊治IgA肾病谈中西医整合(PDF)

《医学争鸣》[ISSN:1000-2790/CN:61-1060/R]

期数:
2020年01期
页码:
29-32,36
栏目:
整合医学
出版日期:
2020-02-29

文章信息/Info

Title:
Integration of traditional Chinese and western medicine in diagnosis and treatment of IgA nephropathy by academician Chen Xiangmei’s team
作者:
黄 锦1李姗姗1杨锦惠2崔银洁3李 丹3郭 义2徐枝芳3
(天津中医药大学: 1实验针灸学研究中心,2中医学院,3针灸推拿学院,天津 301617)
Author(s):
HUANG Jin1 LI Shanshan1 YANG Jinhui2 CUI Yinjie3 LI Dan3 GUO Yi2 XU Zhifang3
1Acupuncture Research Center, 2College of Traditional Chinese Medicine, 3School of Acupuncture and Massage, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
关键词:
IgA肾病中西医整合陈香美院士团队
Keywords:
IgA nephropathy holistic integrative traditional Chinese and western medicine academician Chen Xiangmei’s team
分类号:
R2-031
DOI:
10.13276/j.issn.1674-8913.2020.01.008
文献标识码:
A
摘要:
目前,关于运用中西医理论及方法诊疗临床常见病的相关研究取得一定进展,对于中西 医整合的思想和方法一直在不断地探索。陈香美院士作为我国中西医诊治肾病的先行者,通过总结 陈院士团队诊治IgA肾病的临床研究,发现其中蕴含着中西医整合的内容。在中医证型与临床病理关 系的相关研究中,表明IgA肾病的中医证型由气虚到阳虚的演变过程,在一定程度上能够反映肾脏病理进行性加重的病变过程;将病理与中医证型相关联,施以辨证论治,陈院士团队展开了中药复方 肾乐胶囊治疗IgA肾病脾肺气虚证的疗效及安全性等多项临床试验,表明与福辛普利联合应用,能够 有效降低24 h尿蛋白水平,使纤维蛋白原(FIB)明显下降,凝血酶原时间(PT)明显延长,减轻患 者的肾功能损害程度。陈院士团队将中医宏观辨证与微观检查相结合和中西药联合应用的思想和方 法存在一定的优势,这样的中西医整合模式同样体现在诸多医家的临床实践中,对进一步探究中西 医整合思想具有借鉴性。
Abstract:
At present, some progress has been made in the research on the application of theories and methods of traditional Chinese medicine (TCM) and western medicine in the diagnosis and treatment of common clinical diseases. As a pioneer in the diagnosis and treatment of nephropathy by Chinese and western medicine, academician Chen Xiangmei summarized the clinical research on the diagnosis and treatment of IgA nephropathy by her team, and found that it contained the integration of Chinese and western medicine. In the relevant studies on the relationship between TCM syndromes and clinicopathology, it is shown that the TCM syndromes of IgA nephropathy evolve from qi deficiency to Yang deficiency, which can reflect the progressive aggravation of renal pathology to a certain extent. Associating pathology with TCM syndrome type and treating the disease based on syndrome differentiation, academician Chen’s team conducted a number of clinical trials regarding the curative effect and safety of TCM compound Shenle Capsule in the treatment of IgA nephropathy spleen-lung qi-deficiency syndrome. The trials showed that the combined use with fosinopril could effectively reduce the 24-hour urine protein levels, make the fibrinogen decline obviously, prolong prothrombin time (PT) remarkably, and relieve patients’ renal damage. Academician Chen’s team has certain advantages in combining the macroscopic syndrome differentiation with microscopic examination as well as combining the ideas and methods of TCM and western medicine. This mode of holistic integrative TCM and western medicine is also reflected in the clinical practice of many doctors, which can serve as a reference for further exploring the integration of TCM and western medicine.

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备注/Memo

备注/Memo:
基金项目:中国工程院咨询研究项目(2018-2D-09-06)
通信作者:徐枝芳。Tel:15822881626,E-mail:xuzhifangmsn@hotmail.com
作者简介:黄 锦。硕士生(导师徐枝芳)。研究方向:针效机制研究,肿瘤免疫学。Tel:18903738147,E-mail:Jhuang223@163.com
更新日期/Last Update: 2020-03-09